Basic research plays a crucial role in ophthalmology, as all scientific knowledge is based on its results. The Thursday of the congress will be dedicated all day to basic research.
Results, structures and challenges will be presented. Clinical problems such as childhood myopia or diabetic retinopathy will be examined from different perspectives by clinicians and researchers. This holistic approach makes it possible to combine both perspectives in a meaningful way and to link the latest findings from basic research with relevant clinical issues. This will lead to translational findings and promote future developments in ophthalmology.
Thursday, 25th September 2025, 8:30-9:45
08:30 – 09:45
Raum XV
Highlights in Translational Science: Novel Perspectives in Translational Glaucoma Research
From a clinician scientist perspective: How to translate data from basic research into clinic
Esther M. Hoffmann (Mainz)
About the whale eye and its adaptations for vision in the deep sea
Elena Vecino (Lejona, E)
Through the optic nerve into the brain using A.I.
Dan Milea (Singapur, SGP)
Do06-05 T-cell mediated autoimmunity in glaucoma
Maximilian N. Braun (Boston / Mainz)
10:15-11:30 Uhr
Raum XV
Highlights in Translational Science: Tumours
Donnerstag, 25. September, 10:15 – 11:30
The clinical challenge of UM
Martina Christina Herwig-Carl (Bonn)
Liver-specific microenvironment of UM metastasis
Sarah Coupland (Liverpool, UK)
Tebentafusp in UM metastasis: how it works and how it was developed
Jessica Hassel (Heidelberg)
Clonal determinants of organotropism in metastatic UM
Mathieu Bakhoum (New Haven, USA)
15:00-16:15 Uhr
Raum XV
Highlights in Translational Science: New concepts in gene therapy
Clinical needs for Gene Therapy
Peter Charbel Issa (München)
Gene Therapy in Children with AIPL1-Associated Severe Retinal Dystrophy
Yannick Laich (Freiburg)
Strategies to improve genome editing in neurons
Knut Stieger (Gießen)
Gene therapy for retinal neovascular disease
Martin Spitzer (Hamburg)
16:45-18:00 Uhr
Raum XV
Highlights in Translational Science: Innate Immunity in ocular surface diseases
Research needs for ophthalmology with a focus on immune and vascular targets in eye diseases and introduction of the SFB1607
Verena Prokosch (Köln)
Discovery of dural lymphatic vessels and the lymphatic-like phenotype of Schlemm’s canal
Aleksanteri Aspelund (Helsinki, FIN)
Lymphatic and blood endothelial mechano-regulation in development and disease
Maike Frye (Hamburg)
Harnessing cellular immunity in ocular disease
Jacobus Bosch (Leiden, NL)